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ÀÛ¼ºÀÏ : 15-10-21 18:00
151031_Journal club_ÈñÀç
 ±Û¾´ÀÌ : °ü¸®ÀÚ
Á¶È¸ : 893  
1. A One Precursor One siRNA Model for Pol IV-Dependent siRNA Biogenesis
Zhai et al., 2015, Cell (¼±Á¤)
- ÀÌ ³í¹®À» ÅëÇØ polymerase4°¡ transcriptionÀ» ÁøÇàÇϸ鼭 DNA templateÀÇ methyl-C¸¦ terminationÀ¸·Î ÀÎÁöÇÏ¿© siRNA¸¦ ¸¸µé¾î³»´Â ¿ªÇÒÀÌ ¹àÇôÁ³½À´Ï´Ù.
Polymerase4¿¡ ÀÇÇÑ P4RNA(Poly4-dependent RNA)¿Í siRNAÀÇ biogenesis¸¦ ºñ±³ÇÏ¿´°í Poly4°¡ È°µ¿ÇÏ´Â TSS siteÀÇ À§Ä¡¿Í Ư¡À» ¾Ë¾Æº¸¾Ò½À´Ï´Ù.

2. SCARECROW-LIKE15(SCL15) interacts with HISTONE DEACETYLASE19(HDA19) and is essential for repressing the seed maturation programme
Gao et al., 2015, Nature communication
- ÀÌ ³í¹®À» ÅëÇØ SCL15°¡ seed maturationÀ» inhibitÇϴµ¥ ¸Å¿ì Áß¿äÇÑ factor¶ó´Â °ÍÀ» ¾Ë¾Ò°í embryo-to-seeding development°úÁ¤¿¡ Áß¿äÇÑ factorµéÀÇ expressionÀ» Á¶ÀýÇϴµ¥ HDA19¸¦ ÀÌ¿ëÇÑ´Ù´Â °ÍÀ» º¸¿©ÁÖ¾ú½À´Ï´Ù.
SCL15¿Í HDA19¿ÍÀÇ direct interaction ¹× co-localizationÀ» º¸¿©ÁÖ¾ú°í SCL15 mutant¿¡ È£¸£¸ó ¹× sucrose ó¸®ÇÔÀ¸·Î ÀÎÇÑ plant growthÀÇ º¯È­¿Í embryonic geneÀÇ expression º¯È­¸¦ º¸¿©ÁÖ¾ú½À´Ï´Ù. ±×¸®°í ¸î°³ÀÇ SCL15-HDA19 target geneµµ ¹àÇô³»¾ú½À´Ï´Ù.

3. Downregulation of N-terminal acetylation(NTA) triggers ABA-mediated drought responses in Arabidopsis
Linster et al., 2015, Nature communication
- Nats·Î ÀÎÇÑ NTA´Â eukaroytes¿¡¼­ ÀÚÁÖ ÀϾ´Â protein modificationÀ¸·Î ¾Ë·ÁÁ³À¸³ª ÀÌ°ÍÀÇ Áß¿äÇÔÀº ¾ÆÁ÷ ¹àÈ÷Áö ¸øÇß½À´Ï´Ù. ÀÌ ³í¹®¿¡¼­´Â ½Ä¹°¿¡¼­ NatA¿¡ ÀÇÇÑ NTA°¡ drought stress¿Í °ü·ÃµÇ¾î ÀÖ´Ù´Â °ÍÀ» ¹àÇû°í NatA°¡ ABAÀÇ downstream¿¡¼­ stress Á¶°Ç¿¡ ÀÇÇÑ ½Ä¹°ÀÇ ´ë»ç º¯È­¸¦ º¸¿©ÁÖ·ÁÇÕ´Ï´Ù.
NatA complex mutantÀÇ embryo lethality¿Í ¿©·¯ stress Á¶°Ç¿¡¼­ ºÎÁ·ÇÑ NatAÀÇ ¿µÇâÀ» º¸¿©ÁÖ¾ú½À´Ï´Ù.

4. Elevated CO2-Induced Responses in Stomata Require ABA and ABA Signaling
Chater et al., 2015, Current Biology
- CO2¿¡ ÀÇÇÑ stomataº¯È­¸¦ ABA¿Í ¿¬°áÁöÀº ³í¹®ÀÔ´Ï´Ù. CO2ÀÇ ³óµµ »ó½Â¿¡ ÀÇÇÑ guard cell¿¡¼­ÀÇ ROS ¹ß»ý°ú CO2 ³óµµ»ó½ÂÀÇ ¹ÝÀÀ¿¡ guard cell¿¡¼­ÀÇ ABA signaling°ú biosynthesisÀÇ Á߿伺À» º¸¿©ÁÖ¾ú½À´Ï´Ù.
³í¹®ÀÇ ³»¿ëÀÌ ¸¹±âº¸´Ù´Â ÀÌ ³í¹®ÀÇ °á°ú¸¦ º¸¿©ÁÖ±â À§ÇÑ backgroundÀÇ ¼Ò°³°¡ ´õ ÁÖ°¡ µÉ °Í °°½À´Ï´Ù.

5. Real-time dynamics of peptide ligand–dependent receptor complex formation in planta.
Somssich et al., 2015, Science Signaling
- ÀÌ ³í¹®¿¡¼­´Â peptide signal moleculeÀ» ÀÎÁöÇÑ receptor°¡ ¾î¶°ÇÑ °úÁ¤À» °ÅÄ¡¸ç ¾î¶°ÇÑ ±¸Á¶Àû ȤÀº °áÇÕÀû º¯È­°¡ »ý±â´ÂÁö º¸¿©ÁÖ´Â ³í¹®ÀÔ´Ï´Ù. 2D MFIS¶ó´Â method¸¦ ÅëÇØ protein lifetimeÀÇ º¯È­¸¦ real timeÀ¸·Î º¸¿©ÁÖ°í receptorµéÀÇ real time lifetime º¯È­¿Í anisotropyÀÇ º¯È­¸¦ ÅëÇØ peptide ligand¿¡ ÀÇÇÑ receptor proteinsµéÀÇ complex Á¶ÇÕÀÇ º¯È­¸¦ ´Ü°èº°·Î º¸¿©ÁÖ´Â ³í¹®ÀÔ´Ï´Ù.